
Premiere: March 27, 2005
Status: Season 5 Premieres Fall 2008
Grey's Anatomy is an Emmy, SAG, and Golden Globe award-winning American primetime television medical drama. It debuted on ABC as a midseason replacement on Easter Sunday, March 27, 2005, immediately following the popular Desperate Housewives. The story revolves around Dr. Meredith Grey (Ellen Pompeo), a surgical intern at the fictional Seattle Grace Hospital in Seattle, Washington. The show features an ensemble cast, though Meredith is featured as the central character, providing voice-over narration at the beginning and end of most episodes. The title of the show is a reference to the famous anatomy textbook, Gray's Anatomy.
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Casts

Ellen Pompeo: Meredith Grey

Patrick Dempsey: Derek Shepherd

Sandra Oh: Cristina Yang

Katherine Heigl: Izzie Stevens

T.R. Knight: George O'Malley

Justin Chambers: Alex Karev

Chandra Wilson: Miranda Bailey

Isaiah Washington: Preston Burke

James Pickens Jr.: Richard Webber

Kate Walsh: Addison Shepherd

Sara Ramirez: Callie Torres

Kate Burton: Ellis Grey

Jeffrey Dean Morgan: Denny Duquette

Eric Dane: Mark Sloan

Chyler Leigh: Lexie Grey

Brooke Smith: Erica Hahn